Pragmatic Apparatus – Can pragmatic research, real-world data and digital technologies aid the development of psychedelic medicine?

Cited by Lee Sonogan

A Primer on Psychedelic Medicine and Altered States of Consciousness | Dr.  Leslie Korn

Abstract by Robin L Carhart-Harris, Anne C Wagner, Manish Agrawal, …

Favourable regulatory assessments, liberal policy changes, new research centres and substantial commercial investment signal that psychedelic therapy is making a major comeback. Positive findings from modern trials are catalysing developments, but it is questionable whether current confirmatory trials are sufficient for advancing our understanding of safety and best practice. Here we suggest supplementing traditional confirmatory trials with pragmatic trials, real-world data initiatives and digital health solutions to better support the discovery of optimal and personalised treatment protocols and parameters. These recommendations are intended to help support the development of safe, effective and cost-efficient psychedelic therapy, which, given its history, is vulnerable to excesses of hype and regulation.

Publication: Journal of Psychopharmacology

Pub Date: April 22, 2021 Doi: (Plenty more sections and references in this research article)

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.