Pragmatic Apparatus – A pragmatic view on pragmatic trials

Cited by Lee Sonogan

Figure 1 from Pros and cons of pragmatic clinical trials. | Semantic Scholar

Abstract by Nikolaos A. Patsopoulos, MD; PhD*

Clinical trials have been the main tool used by the health sciences community to test and evaluate interventions. Trials can fall into two broad categories: pragmatic and explanatory. Pragmatic trials are designed to evaluate the effectiveness of interventions in real-life routine practice conditions, whereas explanatory trials aim to test whether an intervention works under optimal situations. Pragmatic trials produce results that can be generalized and applied in routine practice settings. Since most results from exploratory trials fail to be broadly generalizable, the “pragmatic design” has gained momentum. This review describes the concept of pragmatism, and explains in particular that there is a continuum between pragmatic and explanatory trials, rather than a dichotomy. Special focus is put on the limitations of the pragmatic trials, while recognizing the importance for and impact of this design on medical practice.

Keywords: trial, randomized controlled trial, pragmatic, comparative, evidencebased medicine

Publication: NCBI aka National Center for Biotechnology Information (Peer-Reviewed Journal)

Pub Date: 13th Jun, 2011 DOI: 10.31887/DCNS.2011.13.2/npatsopoulos

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181997/ (Full article right here!)

https://ungroovygords.com/

https://entertainmentcultureonline.com/

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.